Confined Bilayers Passively Regulate Shape and Stress

Author (s): M. Staykova; M. Arroyo; M. Rahimi, and H. A. Stone
Journal: Physical Review Letters
Volume: 110
Date: 2013

Lipid membranes are commonly confined to adjacent subcellular structures or to artificial substrates and particles. We develop an experimental and theoretical framework to investigate the mechanics of confined membranes, including the influence of adhesion, strain, and osmotic pressure. We find that supported lipid bilayers respond to stress by nucleating and evolving spherical and tubular protrusions. In cells, such transformations are generally attributed to proteins. Our results offer insights into the mechanics of cell membranes and can further extend the applications of supported bilayers.


  title = {Confined Bilayers Passively Regulate Shape and Stress},
  author = {Staykova, Margarita and Arroyo, Marino and Rahimi, Mohammad and Stone, Howard A.},
  journal = {Phys. Rev. Lett.},
  volume = {110},
  issue = {2},
  pages = {028101},
  numpages = {5},
  year = {2013},
  month = {Jan},
  publisher = {American Physical Society},
  doi = {10.1103/PhysRevLett.110.028101},
  url = {http://link.aps.org/doi/10.1103/PhysRevLett.110.028101}