The current pandemic is affecting our life in many ways. Guillermo Vilanova, Pablo Sáez and Marino Arroyo are used to brainstorming around a whiteboard to devise new mathematical and computational models in mechanobiology. Theoretical research does not justify personal interaction, but as so many around the globe, this team is coping with social distancing through technology, and are currently developing new models to understand why and how cancer organoids become invasive in the context of the EU-funded project MECHANO·CONTROL (http://mechanocontrol.eu). MECHANO·CONTROL focuses on the mechanical control of the biological function with the aim to abrogate breast tumour progression. The project has established an interdisciplinary research community to understand and control cellular mechanics from the molecular to the organism scale. Starting from observations of experimental colleagues in Barcelona, Saarbruecken, London and Utrecht, researchers at LaCàN in UPC develop theoretical models across scales to provide a mechanistic understanding of cancer mechanobiology. They also develop computational technologies that can be broadly valuable to the research community.