Distinguished Researcher (Beatriz Galindo Call, 2018, BEAGAL18/00065) at Universitat Politècnica de Catalunya - Laboratory of Computational Methods and Numerical Analysis (LaCàN Group) - Departament d'Enginyeria Civil i Ambiental - Escola Tècnica Superior d'Enginyers de Camins, Canals i Ports de Barcelona (ETSECCPB) since September 2016.

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Office: Building C2, floor 2, room 203, Campus Nord UPC, Jordi Girona, 1-3, E-08034, Barcelona, Spain

Phone: +34 943015857

Education

Ph.D. (European mention, Cum Laude) in Computational Mechanics, University of Zaragoza (Spain), 2012.

Thesis title: “Experimental and Numerical Framework for Modelling Vascular Diseases and Medical Devices”.

Advisors: Prof. Miguel Ángel Martínez Barca, Prof. Estefanía Peña Baquedano.

 

Sc. Industrial Engineering (Mechanics), University of Oviedo (Spain), 2007.

Master thesis: "Design and validation of a human foot 3D model by the Finite Element Method”, 1st class honors qualification.

Research interests

I develop my research activities in the fields of Numerical Modelling and Simulation: Reduced Order Models (PGD), Metamaterials, Biomechanics, Mechanobiology and Tissue Engineering, Data analysis (SVD, PCA, KPCA), Uncertainty Quantification and research activities with Industrial collaborations (Automotive and Civil industries).

 


Scientific Publications

 

Pedro Díez, Sergio Zlotnik, Alberto García-González, Antonio Huerta. Algebraic PGD for tensor separation and compression: an algorithmic approach. Comptes rendus – Mécanique (2018), Volume 346 Issue 7, 501-514. https://doi.org/10.1016/j.crme.2018.04.011

 

García-González A & Jacchetti E, Marotta R, Tunesi M, Rodríguez Matas JF and Raimondi MT. The Effect of Cell Morphology on the Permeability of the Nuclear Envelope to Diffusive Factors. Frontiers in Physiology (2018)  9:925. doi: 10.3389/fphys.2018.00925

 

Sibileau, A., García-González, A., Auricchio, F., Morganti, S., Díez, P. Explicit parametric solutions of lattice structures with proper generalized decomposition (PGD): Applications to the design of 3D-printed architectured materials. Computational Mechanics (2018) http://dx.doi.org/10.1007/s00466-017-1534-9

 

J. Ohayon, S.K. Yazdani, M. Malvè, A.M. Gharib, J. Heroux, A. García, G. Finet and R.I. Pettigrew.Arterial Wall Stiffness and Atherogenesis in Human Coronaries. (2017) Elsevier Ed. Hardcover ISBN: 9780128040096 (Book Chapter)

 

García A, Matas JF, Raimondi M.T. Modeling of the mechano-chemical behaviour of the Nuclear Pore Complex: Current research and perspective. Integrative Biology, 2016, Integr. Biol. 8, 1011-1021.

 

P. Sáez & A. García, E. Peña, T.C. Gasser, M.A. Martínez. Microstructural quantification of collagen fiber orientations and its integration in constitutive modeling of the porcine carotid artery.Acta Biomaterialia, Volume 33, 15 March 2016, Pages 183–193.

 

Malvè, S. Chandra, A. García, A. Mena, M. A. Martínez, E. A. Finol & M. Doblaré. Impedance-based outflow boundary conditions for human carotid haemodynamics, (2014). Computer methods in Biomechanics and Biomedical Engineering, , 17 (11), pp. 1248-1260

 

A. García, M. A. Martínez and E. Peña. Determination and Modeling of the Inelasticity Over the Length of the Porcine Carotid Artery, (2013). Journal of Biomechanical Engineering. 135 - 3, pp. 031004 – 031013.

 

A. García, S. Lerga, E. Peña, M. Malvè, A. Laborda, M. A. de Gregorio, M. A. Martínez. Evaluation of migration forces of a retrievable filter: Experimental setup and finite element study, (2012). Medical Engineering &Physics. 34, pp. 1167 – 1176.

 

A. García, E. Peña and M. A. Martínez. Influence of geometrical parameters on radial force during self-expanding stent deployment. Application for a variable radial stiffness stent design, (2012). Journal of the Mechanical Behavior of Biomedical Materials. 10, pp. 166 - 175.

 

Malvè, A. García, J. Ohayon and M. A. Martínez. Unsteady blood flow and mass transfer of a human left coronary artery bifurcation: FSI vs. CFD, (2012). International Communications in Heat and Mass Transfer. 39 - 6, pp. 745 - 751.

 

A. García, M. A. Martínez and E. Peña. Viscoelastic properties of the passive mechanical behavior of the porcine carotid artery. Influence of proximal and distal positions, (2012). Biorheology. 49 - 4, pp. 271 - 88.

 

Peña Estefanía, Alberto García, and Miguel Angel Martínez. Viscoelastic and inelastic properties of the porcine carotid artery. Implications in animal cardiovascular device trials. Journal of Biomechanics 45 (2012): S29.

 

A. García, E. Peña, A. Laborda, F. Lostalé, M. A. de Gregorio, M. Doblaré and M. A. Martínez. Experimental study and constitutive modelling of the passive mechanical properties of the porcine carotid artery and its relation to histological analysis: implications in animal cardiovascular device trials, (2011). Medical Engineering &Physics. 33 - 6, pp. 83 - 102.

 

Ohayon, A. M. Gharib, A. García, J. Heroux, S. K. Yazdani, M. Malvè, P. Tracqui, M. A. Martínez, M. Doblaré, G. Finet and R. I. Pettigrew. Is arterial wall-strain stiffening an additional process responsible for atherosclerosis in coronary bifurcations?: in vivo study based on dynamic CT and MRI, (2011). American Journal of Physiology-Heart and Circulatory Physiology. 301 - 3, pp. H1097 - H1106. 

 

Alastrué, A. García, E. Peña, J. F. Rodríguez, M. A. Martínez and M. Doblaré. Numerical framework for patient-specific computational modelling of vascular tissue, (2010). International Journal for Numerical Methods in Biomedical Engineering. 26 - 1, pp. 35 - 51.

 

 A. García-González, J. Bayod, J. C. Prados-Frutos, M. Losa-Iglesias, K. Jules, R. B. de Bengoa-Vallejo and M. Doblaré. Finite element simulation of flexor digitorum longus or flexor digitorum brevis tendon transfer for the treatment of claw toe deformity, (2009). Journal of Biomechanics. 42 - 11, pp. 1697 - 1704.

 

Alberto García González; Carlos Marzo Mainar; Estefanía Peña Baquedano; Miguel Ángel Martínez Barca; Manuel Doblaré Castellano. Device for clamping samples in mechanical tests on soft tissue, (2013). (ES 2379815 B1) (Patent)

 

 

Additional information

 

Teaching Activities

 

Course 2015-2016

PhD course of Mechanobiology - Politecnico di Milano

Computational mechanics and modeling of diffusion process in cells.

 

Course 2016-2017

Métodos Numéricos - Ingeniería Geológica (UPC) 

Modelización Numérica - Ingeniería Geológica (UPC)

Advanced Fluid Mechanics- Master on Numerical Methods in Engineering (UPC) and Master of Science in Computational Mechanics.

Numerical modelling  - Master in Civil Engineering. Camins UPC BarcelonaTech

 

Course 2017-2018

Métodos Numéricos –  Ingeniería Geológica (UPC)

Modelización Numérica –  Ingeniería Geológica (UPC)

Advanced Fluid Mechanics- Master on Numerical Methods in Engineering (UPC) and Master of Science in Computational Mechanics.

Numerical modelling  - Master in Civil Engineering. Camins UPC BarcelonaTech

Academic Coordinator of the Erasmus Mundus Master in Computational Mechanics (MCM)

 

Course 2018-2019

Métodos Numéricos –  Ingeniería Geológica (UPC)

Modelización Numérica –  Ingeniería Geológica (UPC)

Advanced Fluid Mechanics- Master on Numerical Methods in Engineering (UPC) and Master of Science in Computational Mechanics.

Numerical Modelling  - Master in Civil Engineering. Camins UPC BarcelonaTech

Academic Coordinator - 3º de Ingeniería Geológica (UPC)


Participation in R&D&I projects funded in competitive public calls

 

  • Project: “Doctorat Industrial (2017 DI 058)

Leading Researcher:Díez, Pedro

Funding institution: AGAUR  Period 2018-2021

 

  • Project: “Empowered decision-making in simulation-based engineering: Advanced Model Reduction for real-time, inverse and optimization in industrial problem (ADMORE)

Leading Researcher:Huerta, Antonio

Funding institution: European Union Horizon 2020 research and innovation program within the framework of Marie Skłodowska-Curie Actions ITN-ETN. Period 2016-2020

 

  • Project:  “Asimilación de datos para una simulacion ingenieril creible (DPI2017-85139-C2-2-R)

Leading Researcher:Huerta, Antonio / Díez, Pedro

Funding institution: Ministerio de Economía y Competitividad. Period 2018-2020

 

  • Project:“Ingeniería basada en simulación computacional (in-silico) para la toma de decisiones en tiempo real (InSilico)(DPI2014-51844-C2-2R)

Leading Researcher:Huerta, Antonio / Díez, Pedro

Funding institution: Ministerio de Economía y Competitividad. Period 2015-2017

 

  • Project: “NICHOID: Mechanobiology of nuclear import of transcription factors modelled within a bioengineered stem cell niche”

Leading Researcher:Manuela Teresa Raimondi

Funding institution: European Research Council-ERC Consolidator grant. Period 2015-2020

 

  • Project: “Modeling and simulation of aging in arteries due to atherosclerosis” (PRI-AIBDE-2011-1216).

 Leading Researcher:Estefanía Peña Baquedano.

Funding institution: Ministry of Science & Technology. Start date: 01/12/2011End date: 31/08/2012

 

  • Project: “Developing of a computational tool for studying fluid-structure interaction in the cardiovascular field. Application to a new cava vein filter prototype” (DPI2010-20746-C03-01)

Leading Researcher:Miguel Ángel Martínez Barca

Funding institution:Ministry of Science & Technology.Start date: 01/01/2011 End date: 31/08/2012

 

  • Project: “Design and development of a new intravascular device prototype (STENT) with variable radial stiffness for carotid artery stenosis” (DPI2007-63254)

Leading Researcher: Miguel Ángel Martínez Barca

Funding institution: Ministry of Science & Technology. Start date: 01/09/2008End date: 30/09/2010

 

Participation in private R&D&I automotive company projects

 

- Concept/detail desing of Aluminium parts, gating systems and moulds for components of the sub-chassis and the suspensions of vehicles.

- Finite Element Simulations of Aluminium parts belonging to sub-chassis and suspensions of vehicles.

 


Previous Professional Activities

 

  • Postdoctoral Researcher in Computational Mechanics and Mechanobiology at the Laboratory of Biological Structure Mechanics (LaBS) of the Politecnico di Milano. ERC-contract. Milano (Italy). (July 2015 – August 2016)     

                                                                                                    

  • Postdoctoral Researcher in Computational Mechanics (CAD & Finite Element Modelling) and Medical Imaging (MRI-DTI) at the Dublin City University, Dublin (Ireland). (August 2014 – July 2015)                                                                                                          

 

  • Independent Researcher in Mechanics: Collaborations with the Applied Mechanics and Bioengineering Group (AMB) of the Aragon Institute of Engineering Research (I3A) of the University of Zaragoza. (September 2013 - July 2014)

 

  • Freelance: Product Developer and Researcher in Biomechanics, Barcelona, Spain.Mechanical designer and finite element analyst as a engineering consultant for companies in automotive industry. Researcher as external collaborator of the "Applied Mechanics and Bioengineering" group (AMB) of the "Aragón Institute of Engineering Research" (I3A) of the University of Zaragoza (Spain). (March 2012 – August 2013)

 

  • Grant-assisted Researcher (Ph.D. Candidate): Aragon Institute of Engineering Research (I3A), Zaragoza, Spain. Research area: Computational mechanics and finite element simulation (CAD-FEA) of vascular soft tissues, design and analysis of minimally invasive devices (stents and inferior vena cava filters), simulation and computational interaction analysis between nonlinear materials by contact techniques, microestructural study of artery microconstituents by histological microscopy techniques and experimental mechanical analysis and post-processing of vascular soft tissues.(September 2008 - February 2012)

 

  • Researcher in Computational Mechanics: Group of Structural Mechanics and Material Modelling (GEMM-I3A), Zaragoza, Spain. Research area: Computational mechanics, design and finite element analysis applied to biological soft (arteries and veins) and hard (bones) tissues. (April 2007 – August 2008)

 

  • Management Apprentice:GAM (General de Alquiler de Maquinaria), Asturias, Spain. Professional activity: Management apprentice in the North-West Section of the company. (August 2006 - March 2007)

 


International Predoctoral research stays in public R&D&I centers

 

  • Royal Institute of Technology, Kungliga Tekniska högskolan (KTH). Stockholm, Sweden.

Host advisor: Prof. T. Christian Gasser

Project title: “Mechanical characterization of carotid artery tissue by experimental test and the use of polarized light microscopy techniques to measure the collagen fibers orientation.”

 

  • Dynacell Group (Laboratorie TIMC-IMAG), University Joseph Fourier. Grenoble, Rhône-Alpes, France.

Host advisor: Prof. Jacques Ohayon

Project title: “Arterial wall-strain stiffening as an additional process responsible of atherosclerosis in coronary bifurcations.”

 


Conferences

 

Pedro Díez, Sergio Zlotnik, Alberto García-González, Antonio Huerta. Solving multiparametric problems with greedy tensor separation and operations: a least squares PGD approach Fifth International Congress on Multiphysics, Multiscale and Optimization Problems (2018) Bilbao (Spain)

 

Giulia Luraghi, Jose Felix Rodriguez Matas, Alberto García, Claudio Chiastra, Georgios Liappas, Giulio Stefanini and Francesco Migliavacca A patient-specific fluid-structure interaction analysis of TAVI procedure. VIRTUAL PHYSIOLOGICAL HUMAN (VPH2018) Zaragoza (Spain)

 

Vermiglio, A. García, P. Díez, D. Borzacchiello, F. Chinesta. Verification and validation for fast simulation of acoustics and electro-magnetics including data assimilation. 6th European Conference on Computational Mechanics (Solids, Structures and Coupled Problems) 7th European Conference on Computational Fluid Dynamics(ECCM-ECFD 2018) Glasgow (Reino Unido)

 

Giulia Luraghi, José Félix Rodriguez Matas, Alberto García, Claudio Chiastra, Georgios Liappas, Giulio Stefanini, Francesco Migliavacca A fluid-structure interaction patient-specific computational methodology to study aortic roots with native calcified valves. (Poster) EUROPEAN SYMPOSIUM ON VASCULAR BIOMATERIALS (ESVB2017) Strasbourg (France)

 

García, E. Jacchetti, J.F. Rodríguez Matas and M.T. Raimondi. Multiscale Numerical Model of the Strain-Based Permeability of the Nuclear Envelope. Congresso Nazionale SIMAI2016 – Bi-annual congress of the Italian Society of Industrial and Applied Mathematics (SIMAI 2016). Milano, Italy 13-16/09/2016

 

García, R. Marotta, M. Tunesi, M.M. Nava, R. Fedele, E. Jacchetti, J.F. Rodríguez Matas and M.T. Raimondi Mechanobiological modeling of the nuclear pore complex. 12THWORLD CONGRESS ON COMPUTATIONAL MECHANICS WCCM XII-APCOM VI. Seoul, Korea 24-29/07/2016

 

García, R. Marotta, M. Tunesi, M.M. Nava, R. Fedele, E. Jacchetti, J.F. Rodríguez Matas and M.T. Raimond Integrated Experimental/computational approach of the Nuclear Pore Complex. (Poster) EUROPEAN CHAPTER MEETING OF THE TISSUE ENGINEERING AND REGENERATIVE MEDICINE INTERNATIONAL SOCIETY. Uppsala, Sweden 28 June - 1 July, 2016

 

García, R. Marotta, M. Tunesi, M.M. Nava, R. Fedele, E. Jacchetti, J.F. Rodríguez Matas and M.T. Raimondi Experimental/computational approach of the nuclear pore complex mechanics. CONGRESSO DEL GRUPPO NAZIONALE DI BIOINGEGNERIA (GNB-ESB), Naples, Italy. 20-22/06/2016 Best ESB Presentation Award

 

A. Garcia; P. Saez; E. Peña; C. T. Gasser; M. A. Martinez. Microstructural analysis of fiber orientation in swine carotid artery: structural quantification and constitutive modelling. 7TH WORLD CONGRESS OF BIOMECHANICS. Boston, Massachusetts, United States of America. 6-11/07/2014 (accepted for Poster)

 

Mauro Malvè; Alberto García González; Miguel Ángel Martínez Barca. Condiciones de presión basadas en el cálculo de la impedancia para la hemodinámica carotidea. REUNION ANUAL DEL CAPITULO NACIONAL ESPAÑOL ESB. Zaragoza, Aragon, Spain. 10/11/2011

 

Alberto García González; Santiago Lerga; Mauro Malvè; Alicia Laborda; Miguel Ángel de Gregorio; Miguel Ángel Martínez Barca. Evaluation of Migration Forces of a Retrievable Filter: Experimental Setup and Finite Element Study. REUNION ANUAL DEL CAPITULO NACIONAL ESPAÑOL ESB. Zaragoza, Aragon, Spain. 10/11/2011

 

Estefanía Peña Baquedano; Alberto García González; Pablo Saez; Thomas Christian Gasser; Miguel Ángel Martínez Barca. Structural Experimental Characterization and Micro-macro Modelling of Collagen Fiber Distribution in Carotid Arteries. SYMPOSIUM ON COMPUTER MODELS IN BIOMECHANICS: FROM NANO TO MACRO. California, United States of America. 29/08/2011

 

Mauro Malvè; S. Chandra; Alberto García González; Miguel Ángel Martínez Barca; E. Finol; Manuel Doblaré Castellano. FSI Analysis of a Human Carotid Bifurcation under Impedance-Based Boundary Conditions. 2ND INTERNATIONAL CONFERENCE ON COMPUTATIONAL & MATHEMATICAL BIOMEDICAL ENGINEERING. Washington D. C., United States of America30/03/2011

 

Jacques Ohayon; Gharib. A. M.; Alberto García González; Finet G.; Miguel Ángel Martínez Barca; Pettigrew R. I. Endothelial strain distribution in human left main coronary bifurcation: In vivo study based on dynamic CT and MRI measurements. 17TH CONGRESS OF THE EUROPEAN SOCIETY OF BIOMECHANICS (ESB). Edinburgh, United Kingdom.  05/07/2010             

 

Estefanía Peña Baquedano; Victor Alastrué Vera; Alberto García González; Jose Félix Rodríguez Matas; Miguel Ángel Martínez Barca; Manuel Doblaré Castellano. On the Patient-specific computational Modelling of Blood Vessel. IV CONGRESS ON COMPUTATIONAL BIOENGINEERING (ICCB),Bertinoro, Emilia-Romagna, Italy. 16/09/2009

 

Alberto García González; Miguel Ángel Martínez Barca; Estefanía Peña Baquedano; Alicia Laborda; Miguel Ángle de Gregorio; Manuel Doblaré Castellano. Estudio mecánico de la interacción entre stents autoexpandibles de Ni-Ti (Nitinol) sobre tejido cardiovascular en técnicas de angioplastia carotídea. IX CONGRESO DE METODOS NUMERICOS EN LA INGENIERIA. Barcelona, Catalonia, Spain.29/06/2009

 

Mauro Malvè; Jose Félix Rodríguez Matas; Alberto García González; Miguel Ángel Martínez Barca; Jacques Ohayon; Manuel Doblaré Castellano. Fluid Solid Interaction of a Human Left Coronary Artery. Implications of the Shear Stress in arterial Bifurcations for Vascular Diseases. 1ST INTERNATIONAL CONFERENCE ON COMPUTATIONAL & MATHEMATICAL BIOMEDICAL ENGINEERING. Swansea, United Kingdom.  29/06/2009

 

Mauro Malvè; Alberto García González; Miguel Ángel Martínez Barca; Jacques Ohayon; Manuel Doblaré Castellano. Análisis fluidodinámico del flujo sanguíneo en la bifurcación de arteria coronaria izquierda. XXVI CONGRESO ANUAL DE LA SOCIEDAD ESPAÑOLA DE INGENIERIA BIOMEDICA-CASEIB. Valladolid, Castile and León, Spain. 15/10/2008

 

Alberto García González; Estefanía Peña Baquedano; Miguel Ángel Martínez Barca; María Teresa Higuera; Miguel Ángel de Gregorio; Manuel Doblaré Castellano. Estudio experimental y modelado constitutivo de las propiedades mecánicas la arteria carótida de cerdo. XXVI CONGRESO ANUAL DE LA SOCIEDAD ESPAÑOLA DE INGENIERIA BIOMEDICA-CASEIB.  Valladolid, Castile and León, Spain. 15/10/2008

 

Alberto García González; Javier Bayod; Manuel Doblaré Castellano. Estudio de diferentes patologías del pie humano por medio de elementos finitos. XII REUNION DE USUARIOS DE ABAQUS. Bilbao, Basque Country, Spain. 05/11/2007

 


Awards

 

“Extraordinary PhD Thesis Award” (2013), Macro-area of Engineering and Architecture.

Conferring institution: University ofZaragoza, Spain.

 

“Best oral Presentation” of the V CONGRESSO DEL GRUPPO NAZIONALE DI BIOINGEGNERIA (GNB ESB-ITA 2016).

 


Grants and scholarships

 

Formación de Personal Investigador (national FPI grant).Zaragoza, Spain. Conferring institution: Ministry of Science & Innovation,(public).Duration: 4 years. Conferral date: 22/08/2008

Complementary grants for stays abroad parallel to the national FPI program (2010), Zaragoza, Spain. Conferring institution: Ministry of Science & Innovation, (public). Conferral date: 15/09/2010

Complementary grants for stays abroad parallel to the national FPI program (2009), Zaragoza, Spain. Conferring institution: Ministry of Science & Innovation, (public). Conferral date: 15/09/2009