Cell, tissue and organ multiscale mechanobiology 

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Mechanics plays a prominent role in fundamental biological processes at the level of individual cells and of groups of cells forming tissues. Examples include cell division, embryo development, healing processes, or cell migration in cancer invasion. In recent years, vast quantitative data from experiments have demonstrated a tight interaction between mechanics and biological regulation. These observations also suggest that despite the daunting molecular and structural complexity of cells and tissues, there are simple underlying principles that govern their behaviour. We aim at  using theoretical modelling and computer simulations to identify such principles and predict cell, tissue or organ response of biologically active materials

 

Selected Publications

2024

Adjoint-based optimal control of contractile elastic bodies. Application to limbless locomotion on frictional substrates
Bijalwan, A.; Muñoz, J.J.
Computer Methods in Applied Mechanics and Engineering, Vol. 420, Article number: 116697, 2024

Switchable tribology of ferroelectrics
Cho, S.; Gaponenko, I.; Cordero-Edwards, K.; Barceló-Mercader, J.; Arias, I.; Kim, D.; Lichtensteiger, C.; Yeom, J.; Musy, L.; Kim, H.; Min Han, S.; Catalan, G.; Paruch, P.; Hong, S.
Nature Communications, Vol. 1, Article number: , 2024

2020

Nonintrusive Stochastic Finite Elements for Crashworthiness with VPS/Pamcrash
Rocas, M.; García-González, A.; Larráyoz, X.; Díez, P.
Archives of Computational Methods in Engineering, Vol. , Article number: , 2020

Projects

Theses