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Publications by Pablo Sáez

2023

The laminin–keratin link shields the nucleus from mechanical deformation and signalling
Kechagia, Z.; Sáez, P.; Gómez-González, M.; Canales, B.; Viswanadha, S.; Zamarbide, M.; Andreu, I.; Koorman, T.; Beedle, A.E.M.; Elosegui-Artola, A.; Derksen, P.W.B.; Trepat, X.; Arroyo M.; Roca-Cusachs P.
Nature Materials, Vol. , Article number: , 2023

Brain tissue mechanics is governed by microscale relations of the tissue constituents
Sáez, P.; Borau, C; Antonovaite, N.; Franze, K.
Biomaterials, Vol. 301, Article number: 122273, 2023

A computational model for early cell spreading, migration, and competing taxis
Betorz J.; Bokil G.R.; Deshpande, S.M.; Kulkarni, K.; Araya D.R.; Venturini, C.; Sáez, P.
Journal of the Mechanics and Physics of Solids, Vol. 179, Article number: 105390, 2023

A multi-scale clutch model for adhesion complex mechanics
Venturini, C.; Sáez, P.
PLOS Computational Biology, Vol. 19(7), Article number: , 2023

Positive, negative and controlled durotaxis
Sáez, P.; Venturini, C.
Soft Matter, Vol. 19, pp. 2993-3001, 2023

2020

Topological features dictate the mechanics of the mammalian brains
Sáez, P.; Duñó, C.; Sun, L.Y.; Antonovaite, N.; Malvè, M.; Tost, D.; Goriely A.
International Journal of Mechanical Sciences, Vol. 187, Article number: 105914, 2020

A complementary energy approach accommodates scale differences in soft tissues
Saez, P.; Eppell S.J.; Ballarini R.; Rodriguez Matas J.F.
Journal of the Mechanics and Physics of Solids, Vol. 138, Article number: 103895, 2020

2019

Mechanical and Microstructural Behavior of Vascular Tissue
Estefanía Peña, Alberto García, Pablo Sáez, Juan A. Peña, Myriam Cilla, Miguel Angel Martínez
Advances in Biomechanics and Tissue Regeneration, Vol. , pp. 63-78, 2019

Mechanotransmission of haemodynamic forces by the endothelial glycocalyx in a full-scale arterial model
Sáez P.; Gallo, D.; Morbiducci, U.
Royal Society Open Science, Vol. 6, Article number: 6, 2019

Computational modeling of epithelial wound healing: Short and long term chemo-mechanical mechanisms
Roldan, L.; Muñoz, J.J.; Saez, P.
Computer Methods in Applied Mechanics and Engineering, Vol. 350, pp. 28-56, 2019

2018

Fully coupled numerical model of actin treadmilling in the lamellipodium of the cell
Kollepara, K.S.; Mulye, P.D.; Saez P.
International Journal for Numerical Methods in Biomedical Engineering, Vol. 34, Article number: 12, 2018

2017

Mechanics Reveals the Biological Trigger in Wrinkly Fingers
Sáez, P.; Zöllner, A. M.
Annals of biomedical engineering, Vol. 45, pp. 1039-1047, 2017

2016

Bulging Brains
Weickenmeier, J.; Saez, P.; Butler, C. A. M. ; Young P. G.; Gorily, A.; Kuhl, E.
Journal of Elasticity, Vol. , pp. 1-16, 2016

Towards the modelling of ageing and atherosclerosis effects in ApoE-/- mice aortic tissue
Waffenschmidt, T.; Cilla, M.; Saez, P.; Perez, M.M.; Martinez, M.A.; Menzel, A.;Peña, E.
Journal of Biomechanics, Vol. 49, Issue 12, pp. 2390-2397, 2016

Microstructural quantification of collagen fiber orientations and its integration in constitutive modeling of the porcine carotid artery
Saez, P.; Garcia, A.; Peña, E.; Gasser, C.; Martinez, M.A.
Acta Biomaterialia, Vol. 33, pp. 183-193, 2016

2015

Computational modeling of acute myocardial infarction
Saez, P.; Kuhl, E.
Computer Methods in Biomechanics and Biomedical Engineering, Vol. 19, pp. 1107-1115, 2015

A theoretical model of the endothelial cell morphology due to different waveforms
Saez, P.; Malve, M.; Martinez, M.A.
Journal of Theoretical Biology, Vol. 379, pp. 16-23, 2015

Computational model of collagen turnover in carotid arteries during hypertension
Saez, P; Peña, E.; Tarbell, J.M.; Martinez, M.A.
International Journal for Numerical Methods in Biomedical Engineering, Vol. 31, Issue 2, Article number: 2705, 2015

On the Theories and Numerics of Continuum Models for Adaptation Processes in Biological Tissues
Saez, P.
Archives of Computational Methods in Engineering, Vol. 23, pp. 301-322, 2015

2014

A Structural Approach Including the Behavior of Collagen Cross-Links to Model Patient-Specific Human Carotid Arteries
Saez, P.; Peña, E.; Martinez, M.A.
Annals of biomedical engineering, Vol. 42, Issue 6, pp. 1158-1169, 2014

2013

Computational modeling of hypertensive growth in the human carotid artery
Saez, P; Peña, E.; Martinez, M.A.; Kuhl, E.
Computational Mechanics, Vol. 53, Issue 6, pp. 1183-1196, 2013

Hierarchical micro-adaptation of biological structures by mechanical stimuli
Sáez, P.; Pena, E.; Doblaré, M.; Martínez, M.A.
International Journal of Solids and Structures, Vol. 50, Issues 14-15, pp. 2353-2370, 2013

2012

Mathematical modeling of collagen turnover in biological tissue
Sáez, P.; Peña, E.; Martínez, MÁ. and Kuhl, E.
Journal of Mathematical Biology, Vol. 67, Issue 6, pp. 1765-1793, 2012

2011

An anisotropic microsphere-based approach for fiber orientation adaptation in soft tissue
Sáez, P.; Pena, E.; Doblare, M.; Martinez, M.A.
IEEE Transactions on Biomedical Engineering, Vol. 58, Issue 12, pp. 3500-3503, 2011

Anisotropic microsphere-based approach to damage in soft fibered tissue
Sáez, P.; Alastrué, V; Peña, E.; Doblaré, M.; Martínez, M.A.
Biomechanics and Modeling in Mechanobiology, Vol. 11, pp. 595-608, 2011

2010

On the use of the Bingham statistical distribution in microsphere-based constitutive models for arterial tissue
Alastrué, V.; Sáez, P.; Martínez, M.A.; Doblaré, M.
Mechanics Research Communications, Vol. 37, Issue 8, pp. 700-706, 2010